Treatment Protocols

Clinical Protocols

Adjuvant & Neoadjuvant Treatments

5 protocols

Category

Timing

5 protocols

Soft tissueAdjuvant

Adjuvant Radiotherapy for Soft Tissue Sarcoma

Soft tissue sarcoma of the extremity, trunk, and head and neck - intermediate and high grade, post-resection

Adjuvant (post-operative) radiotherapy delivered after surgical resection of soft tissue sarcoma

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BoneNeoadjuvant

Denosumab for Giant Cell Tumour of Bone

Giant cell tumour of bone

Denosumab is a fully human monoclonal antibody targeting RANKL (receptor activator of nuclear factor kappa-B ligand)

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BoneNeoadjuvantSurgeryAdjuvant

MAP Chemotherapy for Osteosarcoma (Methotrexate, Doxorubicin, Cisplatin)

Osteosarcoma (osteoblastic, chondroblastic, fibroblastic, telangiectatic variants), high grade surface osteosarcoma, Paget's sarcoma

MAP (Methotrexate, Doxorubicin/Adriamycin, Cisplatin) is the international standard chemotherapy regimen for high-grade osteosarcoma

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Soft tissueNeoadjuvant

Neoadjuvant Radiotherapy for Soft Tissue Sarcoma

Soft tissue sarcoma of the extremity, trunk, and retroperitoneum - intermediate and high grade

Neoadjuvant (pre-operative) radiotherapy is delivered before surgical resection

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BoneNeoadjuvantSurgeryAdjuvant

VAC/IE Chemotherapy for Ewing Sarcoma (Vincristine, Doxorubicin, Cyclophosphamide / Ifosfamide, Etoposide)

Ewing sarcoma (bone and soft tissue), BCOR-rearranged sarcoma, CIC-rearranged sarcoma (Ewing-like)

VAC/IE (alternating Vincristine-Doxorubicin-Cyclophosphamide / Ifosfamide-Etoposide) is the standard chemotherapy for Ewing sarcoma

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