Synonyms

• AFM
• digital fibromixoma

Category

Soft tissue

Behaviour

Benign

Gender

Male

Tissue of Origin

Fibrous

Epidemiology

• Benign fibromyxoid lesion
• Peak incidence in middle-aged adults

Clinical Features

• Slowly growing nodule on digit
• Often painless
• May cause nail deformity

Location

• Acral: fingers and toes (classic)
• Periungual and subungual region
• Palm of hand and sole of feet

Imaging

• MRI: myxoid mass with fibrosis
• Radiograph: may show Bone erosion

Pathology

Myxoid or collagenous troma with bland fibroblasts

Genetics

Deletion of RB1 gene

Treatment

Marginal excision

Prognosis

Low recurrence if completely excised

Key Points

• Benign acral fibromyxoid tumour with predilection for subungal and periungual regions
• Complete excision prevents recurrence

Workup - Blood Tests

No blood tests required

Workup - Local Imaging

MRI for characterisation

Workup - Biopsy

Excisional biopsy as diagnosis and treatment

Workup - Staging

No staging required

Follow-up Summary

No specific follow up